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The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malign...

The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malign...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_6898275

The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

About this item

Full title

The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

Publisher

Korean Society for Molecular and Cellular Biology

Journal title

Molecules and Cells, 2020, 43(2), , pp.145-152

Language

English

Formats

Publication information

Publisher

Korean Society for Molecular and Cellular Biology

Subjects

Subjects and topics

More information

Scope and Contents

Contents

RUNX1 plays an important role in the regulation of normal hematopoiesis.
RUNX1
mutations are frequently found and have been intensively studied in hematological malignancies. Germline mutations in
RUNX1
cause familial platelet disorder with predisposition to acute myeloid leukemia (FPD/AML). Somatic mutations of
RUNX1
are observed...

Alternative Titles

Full title

The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_6898275

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_nrf_kci_oai_kci_go_kr_ARTI_6898275

Other Identifiers

ISSN

1016-8478

E-ISSN

0219-1032

DOI

10.14348/molcells.2019.0252

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