Structure and mechanism of the UvrA–UvrB DNA damage sensor
Structure and mechanism of the UvrA–UvrB DNA damage sensor
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The bacterial nucleotide excision repair pathway starts with the sensor complex UvrA–UvrB scanning the genome and undergoing conformational change when DNA lesions are detected. Now crystal structures of a UvrA dimer and the UvrA–UvrB complex, along with biochemical analyses, provide insight into these early nucleotide excision repair events.
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Full title
Structure and mechanism of the UvrA–UvrB DNA damage sensor
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TN_cdi_osti_scitechconnect_1037482
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1037482
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2240