Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1
Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Contents
Two-pore domain potassium (K⁺) channels (K2P channels) control the negative resting potential of eukaryotic cells and regulate cell excitability by conducting K⁺ ions across the plasma membrane.Here, we present the 3.4 angstrom resolution crystal structure of a human K2P channel, K2P1 (TWIK-1).Unlike other K⁺ channel structures, K2P1 is dimeric. An...
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Full title
Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1
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TN_cdi_osti_scitechconnect_1109535
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1109535
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1213274
