Synthetic protein scaffolds provide modular control over metabolic flux
Synthetic protein scaffolds provide modular control over metabolic flux
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Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Engineered metabolic pathways are usually devoid of the regulatory mechanisms characteristic of natural metabolism. Using pathways not normally found in
E. coli
, Dueber
et al
. show that synthetic scaffolds built using protein-protein interaction domains can boost yields of mevalonate and glucaric acid.
Engineered metabolic pathways...
Alternative Titles
Full title
Synthetic protein scaffolds provide modular control over metabolic flux
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TN_cdi_osti_scitechconnect_1153311
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1153311
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1557
