Structural insights into the activation of metabotropic glutamate receptors
Structural insights into the activation of metabotropic glutamate receptors
About this item
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Author / Creator
SLAC National Accelerator Lab., Menlo Park, CA (United States) , Koehl, Antoine , Hu, Hongli , Feng, Dan , Sun, Bingfa , Zhang, Yan , Robertson, Michael J. , Chu, Matthew , Kobilka, Tong Sun , Laeremans, Toon , Steyaert, Jan , Tarrasch, Jeffrey , Dutta, Somnath , Fonseca, Rasmus , Weis, William I. , Mathiesen, Jesper M. , Skiniotis, Georgios and Kobilka, Brian K.
Publisher
United States: Nature Publishing Group
Journal title
Language
English
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Publication information
Publisher
United States: Nature Publishing Group
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Scope and Contents
Contents
Metabotropic glutamate receptors are family C G-protein-coupled receptors. They form obligate dimers and possess extracellular ligand-binding Venus flytrap domains, which are linked by cysteine-rich domains to their 7-transmembrane domains. Spectroscopic studies show that signalling is a dynamic process, in which large-scale conformational changes...
Alternative Titles
Full title
Structural insights into the activation of metabotropic glutamate receptors
Authors, Artists and Contributors
Author / Creator
Koehl, Antoine
Hu, Hongli
Feng, Dan
Sun, Bingfa
Zhang, Yan
Robertson, Michael J.
Chu, Matthew
Kobilka, Tong Sun
Laeremans, Toon
Steyaert, Jan
Tarrasch, Jeffrey
Dutta, Somnath
Fonseca, Rasmus
Weis, William I.
Mathiesen, Jesper M.
Skiniotis, Georgios
Kobilka, Brian K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_osti_scitechconnect_1503075
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_1503075
Other Identifiers
ISSN
0028-0836
