A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum
A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum
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Publisher
Washington, DC: American Society for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Society for the Advancement of Science
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Scope and Contents
Contents
A nonlysosomal pathway exists for the degradation of newly synthesized proteins retained within the endoplasmic reticulum (ER). This pathway is extremely selective: whereas some proteins are rapidly degraded, others survive for long periods in the ER. The question of whether this selectivity is due to the presence within the sensitive proteins of d...
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Full title
A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum
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TN_cdi_osti_scitechconnect_6160339
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_6160339
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.2294595