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A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_6160339

A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

About this item

Full title

A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

Publisher

Washington, DC: American Society for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 1990-01, Vol.247 (4938), p.79-82

Language

English

Formats

Publication information

Publisher

Washington, DC: American Society for the Advancement of Science

More information

Scope and Contents

Contents

A nonlysosomal pathway exists for the degradation of newly synthesized proteins retained within the endoplasmic reticulum (ER). This pathway is extremely selective: whereas some proteins are rapidly degraded, others survive for long periods in the ER. The question of whether this selectivity is due to the presence within the sensitive proteins of d...

Alternative Titles

Full title

A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_osti_scitechconnect_6160339

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_osti_scitechconnect_6160339

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.2294595