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Biosensor Analysis of β2-Glycoprotein I–Reactive Autoantibodies: Evidence for Isotype-Specific Bindi...

Biosensor Analysis of β2-Glycoprotein I–Reactive Autoantibodies: Evidence for Isotype-Specific Bindi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_18810989

Biosensor Analysis of β2-Glycoprotein I–Reactive Autoantibodies: Evidence for Isotype-Specific Binding and Differentiation of Pathogenic from Infection-Induced Antibodies

About this item

Full title

Biosensor Analysis of β2-Glycoprotein I–Reactive Autoantibodies: Evidence for Isotype-Specific Binding and Differentiation of Pathogenic from Infection-Induced Antibodies

Publisher

Washington, DC: American Association for Clinical Chemistry

Journal title

Clinical chemistry (Baltimore, Md.), 2007-06, Vol.53 (6), p.1137-1143

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for Clinical Chemistry

More information

Scope and Contents

Contents

Background: For the laboratory diagnosis of the antiphospholipid syndrome (APS) we developed a biosensor with the ability to distinguish between disease-relevant anti-β2-glycoprotein I (β2GPI) autoantibodies (anti-β2GPI) and pathogen-specific β2GPI cross-reactive antibodies that occur transiently during infections.
Methods: We used a surface pla...

Alternative Titles

Full title

Biosensor Analysis of β2-Glycoprotein I–Reactive Autoantibodies: Evidence for Isotype-Specific Binding and Differentiation of Pathogenic from Infection-Induced Antibodies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pascalfrancis_primary_18810989

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_18810989

Other Identifiers

ISSN

0009-9147

E-ISSN

1530-8561

DOI

10.1373/clinchem.2006.079632

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