Log in to save to my catalogue

Development of a High-Throughput Cell-Based Assay for 11β-Hydroxysteroid Dehydrogenase Type 1 Using...

Development of a High-Throughput Cell-Based Assay for 11β-Hydroxysteroid Dehydrogenase Type 1 Using...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_20505560

Development of a High-Throughput Cell-Based Assay for 11β-Hydroxysteroid Dehydrogenase Type 1 Using BacMam Technology

About this item

Full title

Development of a High-Throughput Cell-Based Assay for 11β-Hydroxysteroid Dehydrogenase Type 1 Using BacMam Technology

Publisher

New York: Humana Press Inc

Journal title

Molecular biotechnology, 2008-06, Vol.39 (2), p.127-134

Language

English

Formats

Publication information

Publisher

New York: Humana Press Inc

More information

Scope and Contents

Contents

Cortisol is an important glucocorticoid in humans that regulates many physiological processes. Human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts cortisone to cortisol in vivo and has emerged as an appealing therapeutic target for treating metabolic diseases. Here, we report a sensitive and robust high-throughput (HT) cell-based assa...

Alternative Titles

Full title

Development of a High-Throughput Cell-Based Assay for 11β-Hydroxysteroid Dehydrogenase Type 1 Using BacMam Technology

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pascalfrancis_primary_20505560

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_20505560

Other Identifiers

ISSN

1073-6085

E-ISSN

1559-0305

DOI

10.1007/s12033-008-9050-y

How to access this item