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Antimuscarinic action of doxorubicin does not involve free-radical formation in isolated guinea pig...

Antimuscarinic action of doxorubicin does not involve free-radical formation in isolated guinea pig...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_22570971

Antimuscarinic action of doxorubicin does not involve free-radical formation in isolated guinea pig hearts

About this item

Full title

Antimuscarinic action of doxorubicin does not involve free-radical formation in isolated guinea pig hearts

Publisher

Plattsburgh, NY: National Research Council of Canada

Journal title

Canadian journal of physiology and pharmacology, 2010-01, Vol.88 (1), p.77-81

Language

English

Formats

Publication information

Publisher

Plattsburgh, NY: National Research Council of Canada

More information

Scope and Contents

Contents

It has been proposed that the cardiotoxicity of anthracycline anticancer drugs involves free-radical formation. One early manifestation of toxicity appears to be caused by the antimuscarinic actions of these drugs. Accordingly, we examined whether the antimuscarinic action of one of these drugs, doxorubicin, is altered by antioxidants. In electrica...

Alternative Titles

Full title

Antimuscarinic action of doxorubicin does not involve free-radical formation in isolated guinea pig hearts

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pascalfrancis_primary_22570971

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_22570971

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/Y09-093

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