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The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death

The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_22796944

The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death

About this item

Full title

The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2010-05, Vol.465 (7297), p.497-501

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

INPP4A suppression of excitotoxic neuronal death
Junko Sasaki and colleagues demonstrate a critical role for inositol polyphosphate phosphatase 4A (INPP4A), a PtdIns(3,4)P
2
phosphatase, in maintaining the integrity of the brain. Mice that lack INPP4A have neurodegeneration in the striatum and suffer from severe involuntary movements. They...

Alternative Titles

Full title

The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pascalfrancis_primary_22796944

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_22796944

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature09023

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