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T-type channel blockade impairs long-term potentiation at the parallel fiber–Purkinje cell synapse a...

T-type channel blockade impairs long-term potentiation at the parallel fiber–Purkinje cell synapse a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_28014848

T-type channel blockade impairs long-term potentiation at the parallel fiber–Purkinje cell synapse and cerebellar learning

About this item

Full title

T-type channel blockade impairs long-term potentiation at the parallel fiber–Purkinje cell synapse and cerebellar learning

Publisher

Washington, DC: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (50), p.20302-20307

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences

More information

Scope and Contents

Contents

Ca V3.1 T-type channels are abundant at the cerebellar synapse between parallel fibers and Purkinje cells where they contribute to synaptic depolarization. So far, no specific physiological function has been attributed to these channels neither as charge carriers nor more specifically as Ca ²⁺ carriers. Here we analyze their incidence on synaptic p...

Alternative Titles

Full title

T-type channel blockade impairs long-term potentiation at the parallel fiber–Purkinje cell synapse and cerebellar learning

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pascalfrancis_primary_28014848

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_28014848

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1311686110