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Cooperation of GroEL/GroES and DnaK/DnaJ Heat Shock Proteins in Preventing Protein Misfolding in Esc...

Cooperation of GroEL/GroES and DnaK/DnaJ Heat Shock Proteins in Preventing Protein Misfolding in Esc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_4476334

Cooperation of GroEL/GroES and DnaK/DnaJ Heat Shock Proteins in Preventing Protein Misfolding in Escherichia coli

About this item

Full title

Cooperation of GroEL/GroES and DnaK/DnaJ Heat Shock Proteins in Preventing Protein Misfolding in Escherichia coli

Publisher

Washington, DC: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1992-11, Vol.89 (21), p.10341-10344

Language

English

Formats

Publication information

Publisher

Washington, DC: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Newly synthesized proteins aggregate extensively in Escherichia coli rpoH mutants, which are deficient in the heat shock proteins (hsp). Overproduction of either GroEL and GroES or DnaK and DnaJ prevents aggregation. If expressed together, the four hsp are effective at physiological concentrations. Our data suggest that the GroEL and GroES proteins...

Alternative Titles

Full title

Cooperation of GroEL/GroES and DnaK/DnaJ Heat Shock Proteins in Preventing Protein Misfolding in Escherichia coli

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pascalfrancis_primary_4476334

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pascalfrancis_primary_4476334

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.89.21.10341

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