Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutan...
Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants
About this item
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Author / Creator
ter Meulen, Jan , van den Brink, Edward N , Poon, Leo L. M , Marissen, Wilfred E , Leung, Cynthia S. W , Cox, Freek , Cheung, Chung Y , Bakker, Arjen Q , Bogaards, Johannes A , van Deventer, Els , Preiser, Wolfgang , Doerr, Hans Wilhelm , Chow, Vincent T , de Kruif, John , Peiris, Joseph S. M and Goudsmit, Jaap
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible. For an effective immune prophylaxis in humans, broad coverage of different strains of SARS-CoV and control of potential neutralization escape variants will be required. Combina...
Alternative Titles
Full title
Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants
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Record Identifier
TN_cdi_plos_journals_1288077852
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288077852
Other Identifiers
ISSN
1549-1676,1549-1277
E-ISSN
1549-1676
DOI
10.1371/journal.pmed.0030237
