Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cel...
Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma
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Author / Creator
Lockwood, William W , Chari, Raj , Coe, Bradley P , Thu, Kelsie L , Garnis, Cathie , Malloff, Chad A , Campbell, Jennifer , Williams, Ariane C , Hwang, Dorothy , Zhu, Chang-Qi , Buys, Timon P H , Yee, John , English, John C , Macaulay, Calum , Tsao, Ming-Sound , Gazdar, Adi F , Minna, John D , Lam, Stephen and Lam, Wan L
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Traditionally, non-small cell lung cancer is treated as a single disease entity in terms of systemic therapy. Emerging evidence suggests the major subtypes--adenocarcinoma (AC) and squamous cell carcinoma (SqCC)--respond differently to therapy. Identification of the molecular differences between these tumor types will have a significant impact in d...
Alternative Titles
Full title
Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma
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Record Identifier
TN_cdi_plos_journals_1288091127
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288091127
Other Identifiers
ISSN
1549-1676,1549-1277
E-ISSN
1549-1676
DOI
10.1371/journal.pmed.1000315
