Mining a cathepsin inhibitor library for new antiparasitic drug leads
Mining a cathepsin inhibitor library for new antiparasitic drug leads
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The targeting of parasite cysteine proteases with small molecules is emerging as a possible approach to treat tropical parasitic diseases such as sleeping sickness, Chagas' disease, and malaria. The homology of parasite cysteine proteases to the human cathepsins suggests that inhibitors originally developed for the latter may be a source of promisi...
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Full title
Mining a cathepsin inhibitor library for new antiparasitic drug leads
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TN_cdi_plos_journals_1288103156
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288103156
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ISSN
1935-2735,1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0001023
