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Targeting the Midgut Secreted PpChit1 Reduces Leishmania major Development in Its Natural Vector, th...

Targeting the Midgut Secreted PpChit1 Reduces Leishmania major Development in Its Natural Vector, th...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288114216

Targeting the Midgut Secreted PpChit1 Reduces Leishmania major Development in Its Natural Vector, the Sand Fly Phlebotomus papatasi

About this item

Full title

Targeting the Midgut Secreted PpChit1 Reduces Leishmania major Development in Its Natural Vector, the Sand Fly Phlebotomus papatasi

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2010-11, Vol.4 (11), p.e901-e901

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

During its developmental cycle within the sand fly vector, Leishmania must survive an early proteolytic attack, escape the peritrophic matrix, and then adhere to the midgut epithelia in order to prevent excretion with remnants of the blood meal. These three steps are critical for the establishment of an infection within the vector and are linked to...

Alternative Titles

Full title

Targeting the Midgut Secreted PpChit1 Reduces Leishmania major Development in Its Natural Vector, the Sand Fly Phlebotomus papatasi

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1288114216

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1288114216

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0000901

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