KIR/HLA Pleiotropism: Protection against Both HIV and Opportunistic Infections
KIR/HLA Pleiotropism: Protection against Both HIV and Opportunistic Infections
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The compound genotype KIR3DS1/HLA-B Bw4-80I, which presumably favors natural killer cell activation, has been implicated in protection against HIV disease. We show that this genotype confers dual protection over the course of HIV disease; early direct containment of HIV viral load, and late specific defense against opportunistic infections, but not...
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Full title
KIR/HLA Pleiotropism: Protection against Both HIV and Opportunistic Infections
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TN_cdi_plos_journals_1289027683
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289027683
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.0020079
