Perlecan Maintains Microvessel Integrity In Vivo and Modulates Their Formation In Vitro
Perlecan Maintains Microvessel Integrity In Vivo and Modulates Their Formation In Vitro
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Faculty of Medicine , Department of Clinical Sciences, Lund , Medicinska fakulteten , Tumörmikromiljö , Lund University , Institutionen för kliniska vetenskaper, Lund , Section I , Tumor microenvironment , Lunds universitet , Sektion I , Gustafsson, Erika , Almonte-Becerril, Maylin , Bloch, Wilhelm and Costell, Mercedes
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Perlecan is a heparan sulfate proteoglycan assembled into the vascular basement membranes (BMs) during vasculogenesis. In the present study we have investigated vessel formation in mice, teratomas and embryoid bodies (EBs) in the absence of perlecan. We found that perlecan was dispensable for blood vessel formation and maturation until embryonic da...
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Perlecan Maintains Microvessel Integrity In Vivo and Modulates Their Formation In Vitro
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TN_cdi_plos_journals_1289060216
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289060216
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0053715
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