Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis
Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis
About this item
Full title
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Most cancer cells express high levels of telomerase and proliferate indefinitely. In addition to its telomere maintenance function, telomerase also has a pro-survival function resulting in an increased resistance against DNA damage and decreased apoptosis induction. However, the molecular mechanisms for this protective function remain elusive and i...
Alternative Titles
Full title
Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis
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Record Identifier
TN_cdi_plos_journals_1289060375
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289060375
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0052989
