Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man
Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man
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United States: Public Library of Science
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English
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United States: Public Library of Science
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West Nile virus (WNV) is a re-emerging pathogen that can cause fatal encephalitis. In mice, susceptibility to WNV has been reported to result from a single point mutation in oas1b, which encodes 2'-5' oligoadenylate synthetase 1b, a member of the type I interferon-regulated OAS gene family involved in viral RNA degradation. In man, the human orthol...
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Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man
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TN_cdi_plos_journals_1289063238
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289063238
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1000321
