IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity
IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The innate immune response is essential for controlling West Nile virus (WNV) infection but how this response is propagated and regulates adaptive immunity in vivo are not defined. Herein, we show that IPS-1, the central adaptor protein to RIG-I-like receptor (RLR) signaling, is essential for triggering of innate immunity and for effective developm...
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IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity
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TN_cdi_plos_journals_1289066011
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289066011
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1000757