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IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289066011

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

About this item

Full title

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2010-02, Vol.6 (2), p.e1000757-e1000757

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The innate immune response is essential for controlling West Nile virus (WNV) infection but how this response is propagated and regulates adaptive immunity in vivo are not defined. Herein, we show that IPS-1, the central adaptor protein to RIG-I-like receptor (RLR) signaling, is essential for triggering of innate immunity and for effective developm...

Alternative Titles

Full title

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289066011

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289066011

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1000757

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