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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinas...

Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinas...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289069835

Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

About this item

Full title

Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-01, Vol.8 (1), p.e53533-e53533

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Metformin is used as an anti-diabetic drug. Metformin ameliorates insulin resistance by improving insulin sensitivity in liver and skeletal muscle. Reduced mitochondrial content has been reported in type 2 diabetic muscles and it may contribute to decreased insulin sensitivity characteristic for diabetic muscles. The molecular mechanism behind the...

Alternative Titles

Full title

Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289069835

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289069835

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0053533

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