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Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate

Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289069896

Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate

About this item

Full title

Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-01, Vol.8 (1), p.e53927

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Sphingolipids play a role in the development of emphysema and ceramide levels are increased in experimental models of emphysema; however, the mechanisms of ceramide-related pulmonary emphysema are not fully understood. Here we examine mechanisms of ceramide-induced pulmonary emphysema. Male Sprague-Dawley rats were treated with fenretinide (20 mg/k...

Alternative Titles

Full title

Fenretinide causes emphysema, which is prevented by sphingosine 1-phoshate

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289069896

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289069896

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0053927

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