Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wid...
Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis
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Author / Creator
Holliday, Elizabeth G. , Smith, Albert V. , Cornes, Belinda K. , Buitendijk, Gabriëlle H. S. , Jensen, Richard A. , Sim, Xueling , Aspelund, Thor , Aung, Tin , Baird, Paul N. , Boerwinkle, Eric , Cheng, Ching Yu , van Duijn, Cornelia M. , Eiriksdottir, Gudny , Gudnason, Vilmundur , Harris, Tamara , Hewitt, Alex W. , Inouye, Michael , Jonasson, Fridbert , Klein, Barbara E. K. , Launer, Lenore , Li, Xiaohui , Liew, Gerald , Lumley, Thomas , McElduff, Patrick , McKnight, Barbara , Mitchell, Paul , Psaty, Bruce M. , Rochtchina, Elena , Rotter, Jerome I. , Scott, Rodney J. , Tay, Wanting , Taylor, Kent , Teo, Yik Ying , Uitterlinden, André G. , Viswanathan, Ananth , Xie, Sophia , Vingerling, Johannes R. , Klaver, Caroline C. W. , Tai, E. Shyong , Siscovick, David , Klein, Ronald , Cotch, Mary Frances , Wong, Tien Y. , Attia, John , Wang, Jie Jin and Wellcome Trust Case Control Consortium 2
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Genetic factors explain a majority of risk variance for age-related macular degeneration (AMD). While genome-wide association studies (GWAS) for late AMD implicate genes in complement, inflammatory and lipid pathways, the genetic architecture of early AMD has been relatively under studied. We conducted a GWAS meta-analysis of early AMD, including 4...
Alternative Titles
Full title
Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis
Authors, Artists and Contributors
Author / Creator
Smith, Albert V.
Cornes, Belinda K.
Buitendijk, Gabriëlle H. S.
Jensen, Richard A.
Sim, Xueling
Aspelund, Thor
Aung, Tin
Baird, Paul N.
Boerwinkle, Eric
Cheng, Ching Yu
van Duijn, Cornelia M.
Eiriksdottir, Gudny
Gudnason, Vilmundur
Harris, Tamara
Hewitt, Alex W.
Inouye, Michael
Jonasson, Fridbert
Klein, Barbara E. K.
Launer, Lenore
Li, Xiaohui
Liew, Gerald
Lumley, Thomas
McElduff, Patrick
McKnight, Barbara
Mitchell, Paul
Psaty, Bruce M.
Rochtchina, Elena
Rotter, Jerome I.
Scott, Rodney J.
Tay, Wanting
Taylor, Kent
Teo, Yik Ying
Uitterlinden, André G.
Viswanathan, Ananth
Xie, Sophia
Vingerling, Johannes R.
Klaver, Caroline C. W.
Tai, E. Shyong
Siscovick, David
Klein, Ronald
Cotch, Mary Frances
Wong, Tien Y.
Attia, John
Wang, Jie Jin
Wellcome Trust Case Control Consortium 2
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1289069954
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289069954
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0053830
