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Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289075348

Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

About this item

Full title

Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2010-06, Vol.6 (6), p.e1000955-e1000955

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The IFN-inducible antiviral protein tetherin (or BST-2/CD317/HM1.24) impairs release of mature HIV-1 particles from infected cells. HIV-1 Vpu antagonizes the effect of tetherin. The fate of virions trapped at the cell surface remains poorly understood. Here, we asked whether tetherin impairs HIV cell-to-cell transmission, a major means of viral spr...

Alternative Titles

Full title

Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289075348

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289075348

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1000955

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