Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission
Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The IFN-inducible antiviral protein tetherin (or BST-2/CD317/HM1.24) impairs release of mature HIV-1 particles from infected cells. HIV-1 Vpu antagonizes the effect of tetherin. The fate of virions trapped at the cell surface remains poorly understood. Here, we asked whether tetherin impairs HIV cell-to-cell transmission, a major means of viral spr...
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Full title
Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission
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TN_cdi_plos_journals_1289075348
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289075348
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1000955