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A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynami...

A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynami...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289077646

A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics

About this item

Full title

A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2010-06, Vol.6 (6), p.e1000954-e1000954

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Poxviruses include medically important human pathogens, yet little is known about the specific cellular factors essential for their replication. To identify genes essential for poxvirus infection, we used high-throughput RNA interference to screen the Drosophila kinome for factors required for vaccinia infection. We identified seven genes including...

Alternative Titles

Full title

A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289077646

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289077646

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1000954

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