MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm F...
MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm Formation by Regulating Type 3 Fimbriae Expression
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Author / Creator
Wilksch, Jonathan J. , Yang, Ji , Clements, Abigail , Gabbe, Jacinta L. , Short, Kirsty R. , Cao, Hanwei , Cavaliere, Rosalia , James, Catherine E. , Whitchurch, Cynthia B. , Schembri, Mark A. , Chuah, Mary L. C. , Liang, Zhao-Xun , Wijburg, Odilia L. , Jenney, Adam W. , Lithgow, Trevor and Strugnell, Richard A.
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Klebsiella pneumoniae causes significant morbidity and mortality worldwide, particularly amongst hospitalized individuals. The principle mechanism for pathogenesis in hospital environments involves the formation of biofilms, primarily on implanted medical devices. In this study, we constructed a transposon mutant library in a clinical isolate, K. p...
Alternative Titles
Full title
MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm Formation by Regulating Type 3 Fimbriae Expression
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Record Identifier
TN_cdi_plos_journals_1289086932
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289086932
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1002204
