Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate...
Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Lymphatic endothelial cells (LECs) are differentiated from blood vascular endothelial cells (BECs) during embryogenesis and this physiological cell fate specification is controlled by PROX1, the master regulator for lymphatic development. When Kaposi sarcoma herpes virus (KSHV) infects host cells, it activates the otherwise silenced embryonic endot...
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Full title
Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus
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TN_cdi_plos_journals_1289088071
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289088071
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1002770
