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Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of M...

Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of M...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289091289

Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis

About this item

Full title

Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2012-05, Vol.8 (5), p.e1002691-e1002691

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Tuberculosis, caused by Mycobacterium tuberculosis infection, is a major cause of morbidity and mortality in the world today. M. tuberculosis hijacks the phagosome-lysosome trafficking pathway to escape clearance from infected macrophages. There is increasing evidence that manipulation of autophagy, a regulated catabolic trafficking pathway, can en...

Alternative Titles

Full title

Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289091289

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289091289

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1002691

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