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4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis G...

4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis G...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289109921

4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

About this item

Full title

4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2012-12, Vol.8 (12), p.e1003097-e1003097

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The cell envelope of Mycobacterium tuberculosis, the causative agent of tuberculosis in humans, contains lipids with unusual structures. These lipids play a key role in both virulence and resistance to the various hostile environments encountered by the bacteria during infection. They are synthesized by complex enzymatic systems, including type-I p...

Alternative Titles

Full title

4′-Phosphopantetheinyl Transferase PptT, a New Drug Target Required for Mycobacterium tuberculosis Growth and Persistence In Vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289109921

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289109921

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1003097

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