Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons
Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The striking differences between the clinical symptoms of tetanus and botulism have been ascribed to the different fate of the parental neurotoxins once internalised in motor neurons. Tetanus toxin (TeNT) is known to undergo transcytosis into inhibitory interneurons and block the release of inhibitory neurotransmitters in the spinal cord, causing a...
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Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons
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TN_cdi_plos_journals_1289111252
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289111252
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1003087