Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G
Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G
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Author / Creator
Stanley, David J , Bartholomeeusen, Koen , Crosby, David C , Kim, Dong Young , Kwon, Eunju , Yen, Linda , Cartozo, Nathalie Caretta , Li, Ming , Jäger, Stefanie , Mason-Herr, Jeremy , Hayashi, Fumiaki , Yokoyama, Shigeyuki , Krogan, Nevan J , Harris, Reuben S , Peterlin, Boris Matija and Gross, John D
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Cellular restriction factors help to defend humans against human immunodeficiency virus (HIV). HIV accessory proteins hijack at least three different Cullin-RING ubiquitin ligases, which must be activated by the small ubiquitin-like protein NEDD8, in order to counteract host cellular restriction factors. We found that conjugation of NEDD8 to Cullin...
Alternative Titles
Full title
Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G
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Record Identifier
TN_cdi_plos_journals_1289112098
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289112098
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1003085
