Log in to save to my catalogue

HLA-Cw0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2...

HLA-Cw0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289114731

HLA-Cw0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2 Receptor and Primary NK Cell Function

About this item

Full title

HLA-Cw0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2 Receptor and Primary NK Cell Function

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2012-07, Vol.8 (7), p.e1002805

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Accumulating evidence suggests an important role for Natural Killer (NK) cells in the control of HIV-1 infection. Recently, it was shown that NK cell-mediated immune pressure can result in the selection of HIV-1 escape mutations. A potential mechanism for this NK cell escape is the selection of HLA class I-presented HIV-1 epitopes that allow for th...

Alternative Titles

Full title

HLA-Cw0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2 Receptor and Primary NK Cell Function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289114731

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289114731

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1002805

How to access this item