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The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish trans...

The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish trans...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289116862

The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cells

About this item

Full title

The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cells

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2012-12, Vol.8 (12), p.e1003084-e1003084

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Epstein-Barr Virus (EBV) is an oncogenic γ-herpesvirus that capably establishes both latent and lytic modes of infection in host cells and causes malignant diseases in humans. Nuclear antigen 2 (EBNA2)-mediated transcription of both cellular and viral genes is essential for the establishment and maintenance of the EBV latency program in B lymphocyt...

Alternative Titles

Full title

The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289116862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289116862

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1003084

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