Role of Ubiquitination in IGF-1 Receptor Signaling and Degradation
Role of Ubiquitination in IGF-1 Receptor Signaling and Degradation
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The insulin-like growth factor 1 receptor (IGF-1R) plays numerous crucial roles in cancer biology. The majority of knowledge on IGF-1R signaling is concerned with its role in the activation of the canonical phosphatidyl inositol-3 kinase (PI3K)/Akt and MAPK/ERK pathways. However, the role of IGF-1R ubiquitination in modulating IGF-1R function is an...
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Full title
Role of Ubiquitination in IGF-1 Receptor Signaling and Degradation
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TN_cdi_plos_journals_1289142721
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289142721
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0000340
