Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores
Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores
About this item
Full title
Author / Creator
Funicello, Marcella , Novelli, Michela , Ragni, Maurizio , Vottari, Teresa , Cocuzza, Cesare , Soriano-Lopez, Joaquin , Chiellini, Chiara , Boschi, Federico , Marzola, Pasquina , Masiello, Pellegrino , Saftig, Paul , Santini, Ferruccio , St-Jacques, Rene , Desmarais, Sylvie , Morin, Nicolas , Mancini, Joseph , Percival, M David , Pinchera, Aldo and Maffei, Margherita
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Growing evidences indicate that proteases are implicated in adipogenesis and in the onset of obesity. We previously reported that the cysteine protease cathepsin K (ctsk) is overexpressed in the white adipose tissue (WAT) of obese individuals. We herein characterized the WAT and the metabolic phenotype of ctsk deficient animals (ctsk-/-). When the...
Alternative Titles
Full title
Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores
Authors, Artists and Contributors
Author / Creator
Novelli, Michela
Ragni, Maurizio
Vottari, Teresa
Cocuzza, Cesare
Soriano-Lopez, Joaquin
Chiellini, Chiara
Boschi, Federico
Marzola, Pasquina
Masiello, Pellegrino
Saftig, Paul
Santini, Ferruccio
St-Jacques, Rene
Desmarais, Sylvie
Morin, Nicolas
Mancini, Joseph
Percival, M David
Pinchera, Aldo
Maffei, Margherita
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1289159922
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289159922
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0000683
