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High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer

High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289160449

High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer

About this item

Full title

High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2009-05, Vol.4 (5), p.e5231-e5231

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Many different genetic alterations are observed in cancer cells. Individual cancer genes display point mutations such as base changes, insertions and deletions that initiate and promote cancer growth and spread. Somatic hypermutation is a powerful mechanism for generation of different mutations. It was shown previously that somatic hypermutability...

Alternative Titles

Full title

High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289160449

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289160449

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0005231

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