Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor
Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Orphan nuclear receptors have been instrumental in identifying novel signaling pathways and therapeutic targets. However, identification of ligands for these receptors has often been based on random compound screens or other biased approaches. As a result, it remains unclear in many cases if the reported ligands are the true endogenous ligands,--i....
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Full title
Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor
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TN_cdi_plos_journals_1289181593
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289181593
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0005609