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Loss of Ribosomal Protein L11 Affects Zebrafish Embryonic Development through a p53-Dependent Apopto...

Loss of Ribosomal Protein L11 Affects Zebrafish Embryonic Development through a p53-Dependent Apopto...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289482468

Loss of Ribosomal Protein L11 Affects Zebrafish Embryonic Development through a p53-Dependent Apoptotic Response

About this item

Full title

Loss of Ribosomal Protein L11 Affects Zebrafish Embryonic Development through a p53-Dependent Apoptotic Response

Publisher

United States: Public Library of Science

Journal title

PloS one, 2009-01, Vol.4 (1), p.e4152-e4152

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Ribosome is responsible for protein synthesis in all organisms and ribosomal proteins (RPs) play important roles in the formation of a functional ribosome. L11 was recently shown to regulate p53 activity through a direct binding with MDM2 and abrogating the MDM2-induced p53 degradation in response to ribosomal stress. However, the studies were perf...

Alternative Titles

Full title

Loss of Ribosomal Protein L11 Affects Zebrafish Embryonic Development through a p53-Dependent Apoptotic Response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1289482468

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289482468

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0004152

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