Deletion of the Mitochondrial Flavoprotein Apoptosis Inducing Factor (AIF) Induces β-Cell Apoptosis...
Deletion of the Mitochondrial Flavoprotein Apoptosis Inducing Factor (AIF) Induces β-Cell Apoptosis and Impairs β-Cell Mass
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Apoptosis is a hallmark of beta-cell death in both type 1 and type 2 diabetes mellitus. Understanding how apoptosis contributes to beta-cell turnover may lead to strategies to prevent progression of diabetes. A key mediator of apoptosis, mitochondrial function, and cell survival is apoptosis inducing factor (AIF). In the present study, we investiga...
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Full title
Deletion of the Mitochondrial Flavoprotein Apoptosis Inducing Factor (AIF) Induces β-Cell Apoptosis and Impairs β-Cell Mass
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TN_cdi_plos_journals_1289786320
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1289786320
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0004394
