IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein
IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The recently identified member of the TNF superfamily TL1A (TNFSF15) increases IFN-gamma production by T cells in peripheral and mucosal CCR9+ T cells. TL1A and its receptor DR3 are up-regulated during chronic intestinal inflammation in ulcerative colitis and Crohn's disease (CD). TL1A gene haplotypes increase CD susceptibility in Japanese, Europea...
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Full title
IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein
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TN_cdi_plos_journals_1290367306
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1290367306
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0004719
