Coordinated Activation of Candidate Proto-Oncogenes and Cancer Testes Antigens via Promoter Demethyl...
Coordinated Activation of Candidate Proto-Oncogenes and Cancer Testes Antigens via Promoter Demethylation in Head and Neck Cancer and Lung Cancer
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Author / Creator
Smith, Ian M. , Glazer, Chad A. , Mithani, Suhail K. , Ochs, Michael F. , Sun, Wenyue , Bhan, Sheetal , Vostrov, Alexander , Abdullaev, Ziedulla , Lobanenkov, Victor , Gray, Andrew , Liu, Chunyan , Chang, Steven S. , Ostrow, Kimberly L. , Westra, William H. , Begum, Shahnaz , Dhara, Mousumi and Califano, Joseph
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Epigenetic alterations have been implicated in the pathogenesis of solid tumors, however, proto-oncogenes activated by promoter demethylation have been sporadically reported. We used an integrative method to analyze expression in primary head and neck squamous cell carcinoma (HNSCC) and pharmacologically demethylated cell lines to identify aberrant...
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Full title
Coordinated Activation of Candidate Proto-Oncogenes and Cancer Testes Antigens via Promoter Demethylation in Head and Neck Cancer and Lung Cancer
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Record Identifier
TN_cdi_plos_journals_1291058154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291058154
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0004961
