Impact of Chromatin Structures on DNA Processing for Genomic Analyses
Impact of Chromatin Structures on DNA Processing for Genomic Analyses
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Chromatin has an impact on recombination, repair, replication, and evolution of DNA. Here we report that chromatin structure also affects laboratory DNA manipulation in ways that distort the results of chromatin immunoprecipitation (ChIP) experiments. We initially discovered this effect at the Saccharomyces cerevisiae HMR locus, where we found that...
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Full title
Impact of Chromatin Structures on DNA Processing for Genomic Analyses
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TN_cdi_plos_journals_1291075399
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291075399
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0006700
