Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper...
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Interactions between B and T cells are essential for most antibody responses, but the dynamics of these interactions are poorly understood. By two-photon microscopy of intact lymph nodes, we show that upon exposure to antigen, B cells migrate with directional preference toward the B-zone-T-zone boundary in a CCR7-dependent manner, through a region...
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Full title
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells
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TN_cdi_plos_journals_1291079972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291079972
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.0030150
