Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4
Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Several Ca(2+)-permeable channels, including the non-selective cation channel TRPV4, are subject to Ca(2+)-dependent facilitation. Although it has been clearly demonstrated in functional experiments that calmodulin (CaM) binding to intracellular domains of TRP channels is involved in this process, the molecular mechanism remains elusive. In this st...
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Full title
Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4
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TN_cdi_plos_journals_1291895047
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291895047
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0010580
