In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stab...
In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability
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United States: Public Library of Science
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English
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United States: Public Library of Science
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It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspected roles in events that might compromise genomic integrity. Here we show both ex vivo and in vivo th...
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In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability
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TN_cdi_plos_journals_1291895077
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291895077
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1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.0050043