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In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stab...

In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stab...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291895077

In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability

About this item

Full title

In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2007-03, Vol.5 (3), p.e43-e43

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspected roles in events that might compromise genomic integrity. Here we show both ex vivo and in vivo th...

Alternative Titles

Full title

In Vivo Reinsertion of Excised Episomes by the V(D)J Recombinase: A Potential Threat to Genomic Stability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1291895077

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291895077

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.0050043

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