Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model o...
Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Dissociating glucocorticoid receptor (GR) ligands hold great promise for treating inflammatory disorders since it is assumed that they exert beneficial activities mediated by transrepression but avoid adverse effects of GR action requiring transactivation. Here we challenged this paradigm by investigating 2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethyl...
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Therapeutic and Adverse Effects of a Non-Steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis
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TN_cdi_plos_journals_1291895680
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1291895680
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0008202