Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical divisions. In vivo, however, stem cells are generally thought to depend on specialised cellular microenvironments and to undergo predominantly asymmetric divisions. Ex vivo expansion of pure populations of tissue stem cells has proven elusive. Neural progenito...
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Full title
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
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TN_cdi_plos_journals_1292063745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292063745
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.0030283
