MISC-1/OGC Links Mitochondrial Metabolism, Apoptosis and Insulin Secretion
MISC-1/OGC Links Mitochondrial Metabolism, Apoptosis and Insulin Secretion
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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We identified MISC-1 (Mitochondrial Solute Carrier) as the C. elegans orthologue of mammalian OGC (2-oxoglutarate carrier). OGC was originally identified for its ability to transfer α-ketoglutarate across the inner mitochondrial membrane. However, we found that MISC-1 and OGC are not solely involved in metabolic control. Our data show that these or...
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MISC-1/OGC Links Mitochondrial Metabolism, Apoptosis and Insulin Secretion
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TN_cdi_plos_journals_1292101605
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292101605
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0017827
