Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Prot...
Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein
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Author / Creator
Das, Debanu , Hervé, Mireille , Feuerhelm, Julie , Farr, Carol L. , Chiu, Hsiu-Ju , Elsliger, Marc-André , Knuth, Mark W. , Klock, Heath E. , Miller, Mitchell D. , Godzik, Adam , Lesley, Scott A. , Deacon, Ashley M. , Mengin-Lecreulx, Dominique , Wilson, Ian A. and SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Bacterial cell walls contain peptidoglycan, an essential polymer made by enzymes in the Mur pathway. These proteins are specific to bacteria, which make them targets for drug discovery. MurC, MurD, MurE and MurF catalyze the synthesis of the peptidoglycan precursor UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-diaminopimelyl-D-alanyl-D-alanine by...
Alternative Titles
Full title
Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein
Authors, Artists and Contributors
Author / Creator
Hervé, Mireille
Feuerhelm, Julie
Farr, Carol L.
Chiu, Hsiu-Ju
Elsliger, Marc-André
Knuth, Mark W.
Klock, Heath E.
Miller, Mitchell D.
Godzik, Adam
Lesley, Scott A.
Deacon, Ashley M.
Mengin-Lecreulx, Dominique
Wilson, Ian A.
SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States). Stanford Synchrotron Radiation Lightsource (SSRL)
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Record Identifier
TN_cdi_plos_journals_1292103352
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292103352
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0017624